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The worth of creating extensive, tissue-specific maps of protein lysine acetylation websites is further underscored by the significant role of posttranslational modifications within the evolution and phenotypic composition of vertebrates, as indicated by the numerous selective stress gene regulatory parts near posttranslational-modifying enzymes have come below in placental animals ( Lowe et al., 2011 ). |
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Amongst them we recognized histone H3 lysine 27 acetylation (H3K27Ac) as a modification upregulated in CRC |
