Our bodies use amino acids to interrupt down long chains or proteins, and then reassemble them into useful merchandise reminiscent of L-Carnitine. The exception to the rule is the DOT1 family, members of which methylate K79 within the globular area of histone H3 and which are structurally not related to SET-area proteins four - 6 Current work suggests that SET-domain-containing proteins methylate a number of proteins in addition to histones (see later)